By Cotton, R., et al. Abstract Digital technology has the potential to transform mental health services. This report examines what the digital revolution means for…
By Christopher A. Longhurst, Robert A. Harrington and Nigam H. Shah. Abstract Randomized controlled trials have traditionally been the gold standard against which all other…
By Jeffrey G Klann , Michael D Buck , Jeffrey Brown , et al. Abstract Objective Understanding population-level health trends is essential to effectively…
By Mandl KD, Kohane IS, McFadden D, et al. Abstract We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable…
By Anita Charlesworth. In the UK, spending on health care has increased by four per cent per year, since the NHS was founded 65 years…
By Faden, Ruth R., Tom L. Beauchamp, and Nancy E. Kass. Abstract Interest in learning health care systems and in comparative-effectiveness research (CER) is…
By El Fadly, AbdenNaji et al. Abstract BackgroundThere are different approaches for repurposing clinical data collected in the Electronic Healthcare Record (EHR) for use in…
By Walsh, T., et al. Abstract Objective To perform a systematic review of studies that assessed the potential of patient decision support interventions (decision aids)…
By Rachel L Richesson et al. Abstract Widespread sharing of data from electronic health records and patient-reported outcomes can strengthen the national capacity for conducting…
By Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, et al. Abstract ObjectiveTo optimally leverage the scalability and unique features of the electronic…
By Luchenski SA, Reed JE, Marston C, Papoutsi C, Majeed A, Bell D. AbstractBackground:The development and implementation of electronic health records (EHRs) remains an international…
By Richesson RL, Hammond WE, Nahm M, et al. Abstract Widespread sharing of data from electronic health records and patient-reported outcomes can strengthen the…
By Faden, Ruth, et al. Abstract Background:Electronic clinical data (ECD) will increasingly serve as an important source of information for comparative effectiveness research (CER). Although…
By Klann, J. G., & Murphy, S. N. ABSTRACT Background: The Health Quality Measures Format (HQMF) is a Health Level 7 (HL7) standard for expressing…
By Lewis, G., et al. Abstract Health care systems in many countries are using the “Triple Aim”–to improve patients' experience of care, to advance population…
By Loder, Bunt, Wyatt. Abstract The way we create, access and share information is changing rapidly. Every time we look something up on Wikipedia, rate…
By Michie, S., et al. Abstract CONSORT guidelines call for precise reporting of behavior change interventions: we need rigorous methods of characterizing active content of…
By McMurry AJ, Murphy SN, MacFadden D, Weber G, Simons WW, et al. Abstract Results of medical research studies are often contradictory or cannot be…
By Kass, N. E., Faden, R. R., Goodman, S. N., Pronovost, P., Tunis, S. and Beauchamp, T. L. Abstract The rise of quality improvement research…
By Solomon, M. Z. and Bonham, A. C. Abstract The Institute of Medicine has called on health care leaders to transform their health systems into…
By Ruth R. Faden, Nancy E. Kass, Steven N. Goodman, Peter Pronovost, Sean Tunis, and Tom L. Beauchamp. Abstract Calls are increasing for American health…
By Greene SM, Reid RJ, Larson EB. Clinicians and health systems are facing widespread challenges, including changes in care delivery, escalating health care costs, and…
By Kenneth D Mandl , Joshua C Mandel , Shawn N Murphy, et al. AbstractObjective: The Substitutable Medical Applications, Reusable Technologies (SMART) Platforms project seeks…
By Charles Friedman, Michael Rigby. Abstract In any country the health sector is important in terms of human wellbeing and large in terms of economics.…
By Yu, M., Xie, D., Wang, X., Weiner, M. G. and Tannen, R. L. ABSTRACTPurposeThe purpose of this study was to evaluate a statistical method,…
By Greenfield, S. and R. Platt Abstract “It is the position of this Task Force that rigorous well designed and well executed Observational Studies (OS)…
By Berger, M. L., et al. Abstract OBJECTIVE: In both the United States and Europe there has been an increased interest in using comparative effectiveness…
By Harcourt, S. E., et al. Abstract The Health Protection Agency/QSurveillance national surveillance system utilizes QSurveillance®, a recently developed general practitioner database covering over 23…
By Delaney B, Peterson K A., Speedie S, Taweel A, Arvanitis T, Hobbs R. Abstract PURPOSE: The learning health care system refers to the cycle…
By Jennifer Frankovich, M.D., Christopher A. Longhurst, M.D., and Scott M. Sutherland, M.D. Abstract Pediatricians facing critical clinical decisions often lack data on which to draw.…
By Michie, S., et al. Abstract Background Improving the design and implementation of evidence-based practice depends on successful behaviour change interventions. This requires an appropriate…
By Appleby, et al. Variations in health care in the NHS are a persistent and ubiquitous problem. But which variations are acceptable or warranted –…
By C. P. Friedman, A. K. Wong, D. Blumenthal. Abstract We outline the fundamental properties of a highly participatory rapid learning system that can…
By Charles P. Friedman, Adam K. Wong and David Blumenthal Abstract We outline the fundamental properties of a highly participatory rapid learning system that…
By Lewis, G. H. Abstract Context: Predictive models can be used to identify people at high risk of unplanned hospitalization, although some of the high-risk…
By Brown, J. et al. Abstract BACKGROUND: Comparative effectiveness research, medical product safety evaluation, and quality measurement will require the ability to use electronic health…
By Institure of Medicine. Abstract The United States has the highest per capita spending on health care of any industrialized nation. Yet despite the unprecedented…
By Bradley, E. H., et al. BackgroundDespite decades of efforts to improve quality of health care, poor performance persists in many aspects of care. Less…
By Tannen Richard L, Weiner Mark G, Xie Dawei. Abstract Objectives To determine whether observational studies that use an electronic medical record database can provide…
By Miller, F. G. Abstract Observational research involving access to personally identifiable data in medical records has often been conducted without informed consent, owing to…
By Sanson-Fisher, R. W., et al. Abstract Population- and systems-based interventions need evaluation, but the randomized controlled trial (RCT) research design has significant limitations when…
By Lynn M. Etheredge. Abstract Private- and public-sector initiatives, using electronic health record (EHR) databases from millions of people, could rapidly advance the U.S. evidence…
By Johnston, S. C., et al. Abstract BACKGROUND: Few attempts have been made to estimate the public return on investment in medical research. The total…
By Kawamoto, K., et al. Abstract Objective To identify features of clinical decision support systems critical for improving clinical practice. Design Systematic review of randomised…
By Rothwell, P. M. Abstract In making treatment decisions, doctors and patients must take into account relevant randomised controlled trials (RCTs) and systematic reviews. Relevance…
By Matzen P. INTRODUCTION: In the early 1990es, it was supposed that only 10-15 per cent of medical interventions were based on results from randomised…
By Mann, C. J. Abstract Cohort, cross sectional, and case-control studies are collectively referred to as observational studies. Often these studies are the only practicable…
By Helms, P. J. Abstract Although the explanatory clinical therapeutic trial remains the foundation for assessing drug efficacy and is required for licensing purposes, the…
By Sibbald, B. and M. Roland. Abstract Randomised controlled trials are the most rigorous way of determining whether a cause-effect relation exists between treatment and…
By Black, N. Abstract The view is widely held that experimental methods (randomised controlled trials) are the “gold standard” for evaluation and that observational methods…